Research

A pharmacy technician checking stocks at a hospital pharmacy

Responding to disruptions in the pharmaceutical supply chainSubscription

By

Economic, manufacturing and regulatory factors can affect drug shortages and supply chain disruption. By using a mixed-methods approach involving an online survey, semi-structured interviews and three targeted focus groups aimed at acute care hospitals in England, Wales, Northern Ireland and Ireland, this study determined that over half of the responding acute care hospitals did not have 76–100% of medicine lines fulfilled within 8 weeks of a disruption in the supply chain.

Insight

close up woman's hand holding asthma inhaler

UK asthma mortality is too high, but pharmacy can helpSubscription

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Since many deaths from asthma could be prevented with the correct treatment, pharmacists should have a greater role in ensuring patients receive the right medicines and referring patients who do not have well-controlled asthma.

CPD article

Angiogram of a calf showing deep vein thrombosis

Prevention of venous thromboembolism in hospitalised patientsSubscription

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Pharmacists should note the National Institute for Health and Care Excellence’s updated guidance on use of pharmacological thromboprophylaxis in a range of hospitalised patient groups.

Research briefing

Physician testing spasticity in motor neurone patient

Cannabinoids could help manage spasticity in motor neurone diseaseSubscription

28 JAN 2019

An oral spray containing cannabinoids is effective at reducing spasticity symptoms in motor neurone disease, study results have shown.

A doctor checking a mamogram for breast cancer

Palbociclib slows tumour growth in early breast cancerSubscription

25 JAN 2019

Adding the CDK4/6 inhibitor palbociclib to hormone therapy can slow or stop tumour growth in women with early breast cancer, a study in the Journal of Clinical Oncology has shown.

Dosette tray drug weekly planner

Increased intensity adherence maximises statin benefitsSubscription

16 JAN 2019

High adherence to intensive lipid-lowering therapy provides the greatest risk reduction for cardiovascular events, a study in JAMA Network Open has shown.

Micrograph of non small cell lung carcinoma

First-line immunotherapy does not improve survival in metastatic lung cancerSubscription

14 JAN 2019

Single or combination first-line immunotherapy does not significantly extend survival compared with chemotherapy in metastatic non small-cell lung carcinoma, trial results have shown.

Short communications

Working with schools to help young people and their families stop smokingSubscription

Smoking remains the single biggest preventable cause of ill health and premature death in Wales[1], and a significant cause of health inequality. Pembroke Dock, a town in south-west Wales, has a population of around 10,000 people. ...

A simple multifunctional tool for integrated care of COPDSubscription

Chronic obstructive pulmonary disease (COPD) affects around 1.2 million people in the UK and has an impact across NHS services[1]. Patients frequently present acutely in the emergency department with an exacerbation of the disease and rely heavily on community ...

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