Needle and syringe programmes cost effective in reducing HCV transmissionSubscription
Study shows needle and syringe programmes reduce transmission of hepatitis C while delivering cost savings.
Long-term follow-up allays fears that finasteride increases mortality Subscription
Initial concerns that finasteride could increase risk of prostate cancer death have been found to be unwarranted in a long-term follow-up study.
Naltrexone not associated with serious adverse events, review findsSubscription
The opioid antagonist naltrexone does not appear to increase the risk of serious adverse events over placebo, researchers from the University of Manchester have found.
Study questions link between antidepressants and hip fracturesSubscription
A previously identified link between antidepressant use and hip fractures needs further examination, the authors of a study published in JAMA Psychiatry have concluded.
Monthly vitamin D dosing has no significant effect on bone mineral densitySubscription
Monthly dosing of vitamin D3 supplements in older adults does not increase bone mineral density, the results of a recent study show.
Patient-centred clinic improves outcomes after myocardial infarctionSubscription
A post-myocardial infarction medicines optimisation clinic, led primarily by a pharmacist with support from a cardiologist, has resulted in improved medicines adherence and guideline concordance, study results published in Open Heart show.
Uncertainty on long-term efficacy of osteoarthritis medicinesSubscription
There is a lack of evidence that medicines for osteoarthritis are effective in the long term, according to a review in the Journal of the American Medical Association.
Sulfonylureas and basal insulin linked to elevated cardiovascular riskSubscription
Sulfonylureas and basal insulin confer an increased risk of cardiovascular events compared with newer second-line medicines for type 2 diabetes mellitus, research has found.
Statins and metformin could be used to treat serious mental illnessSubscription
Existing medicines for physical conditions such as diabetes and hypertension could be used to treat serious mental illness, concluded the authors of a recent study in JAMA Psychiatry.
Cannabinoids could help manage spasticity in motor neurone diseaseSubscription
An oral spray containing cannabinoids is effective at reducing spasticity symptoms in motor neurone disease, study results have shown.
Palbociclib slows tumour growth in early breast cancerSubscription
Adding the CDK4/6 inhibitor palbociclib to hormone therapy can slow or stop tumour growth in women with early breast cancer, a study in the Journal of Clinical Oncology has shown.
BMI is an effective indicator of cardiometabolic health, researchers saySubscription
A study of adolescents supports the use of body mass index measurement as a helpful tool for detecting the metabolic and cardiovascular effects of obesity.
Fluoxetine does not assist recovery following stroke, research suggestsSubscription
Daily fluoxetine in patients who have had a stroke does not improve functional outcomes at six months, results of a randomised trial published in The Lancet have shown.
Increased intensity adherence maximises statin benefitsSubscription
High adherence to intensive lipid-lowering therapy provides the greatest risk reduction for cardiovascular events, a study in JAMA Network Open has shown.
First-line immunotherapy does not improve survival in metastatic lung cancerSubscription
Single or combination first-line immunotherapy does not significantly extend survival compared with chemotherapy in metastatic non small-cell lung carcinoma, trial results have shown.
Exercise may be as effective as medicines in hypertensionSubscription
Exercise interventions are as effective in reducing systolic blood pressure as many antihypertensive medicines in people with hypertension, according to the results of a network meta-analysis published in the British Journal of Sports Medicine.
Smokers who use e-cigarettes no more likely to quit in the long term, study findsSubscription
People who use e-cigarettes alongside traditional cigarettes are no more likely to quit smoking in the long term than those who only smoke cigarettes, research has shown.
Depression linked to atrial fibrillation diagnosisSubscription
Depression is associated with an increased likelihood of atrial fibrillation diagnosis, according to a study published in the European Journal of Preventive Cardiology.
Obesity increases risk of childhood asthma by 29%, say researchersSubscription
Obesity is a major preventable cause of childhood asthma, conclude the authors of a study published in Paediatrics.
