Androgen deprivation therapy 'increases heart failure risk'Subscription
Patients with prostate cancer treated with androgen deprivation therapy were 72% more likely to experience heart failure than those unexposed to the therapy, a study has shown.
Neurotransmitter-affecting medicines used in pregnancy not linked to autism risk in offspringSubscription
Maternal use of medicines targeting neurotransmitter systems is unlikely to directly affect the risk of autism spectrum disorder in offspring, the authors of a study published in JAMA Psychiatry have concluded.
First-year statin discontinuation and non-adherence common in older adultsSubscription
A substantial proportion of older people who begin taking statins do not take them as intended, according to an Australian study published in the British Journal of Clinical Pharmacology.
ACEIs linked to increased risk of lung cancerSubscription
An observational study of almost one million people suggests a link between angiotensin converting enzyme inhibitors and an increased risk of lung cancer.
Cannabinoids have limited impact on MS symptomsSubscription
Following a systematic review and meta-analysis researchers have concluded that cannabinoids have limited therapeutic effect on symptoms of multiple sclerosis
Raised urate levels more strongly linked to genetics than diet, study findsSubscription
Diet contributes much less towards the development of high serum urate levels than genetic factors, study results reported in The BMJ suggest.
Triple therapy cuts exacerbations in COPD regardless of baseline reversibilitySubscription
Triple therapy reduces the number of moderate-to-severe exacerbations in people with chronic obstructive pulmonary disease, a study presented at the CHEST annual meeting has shown.
Weight loss drug reduces risk of diabetes in overweight and obese peopleSubscription
Taking lorcaserin and making lifestyle changes can help prevent diabetes in people who are overweight or obese, study findings indicate.
New antibiotic effective against multi-drug resistant Gram-negative UTISubscription
A new antibiotic designed to overcome multi-drug resistance is at least as effective as the current standard of care in complicated urinary tract infection, according to trial results published in The Lancet Infectious Diseases.
Low-dose aspirin cuts ovarian cancer riskSubscription
Use of low-dose aspirin is associated with a reduced risk of ovarian cancer, results from a cohort study show.
Durvalumab increases overall survival in stage III non-small-cell lung cancerSubscription
The immune checkpoint inhibitor durvalumab significantly improves survival in people with stage III non-small-cell lung cancer, interim trial results published in The New England Journal of Medicine have shown.
Major study boosts knowledge of blood pressure geneticsSubscription
A study has found over 500 genetic regions, known as loci, that are associated with blood pressure characteristics and researchers say the information could enable high-risk individuals to be targeted earlier for hypertension prevention.
Newer hormonal contraceptives still associated with reduced risk of ovarian cancerSubscription
Researchers in Denmark found that newer combined hormonal contraceptives were still associated with a reduction in ovarian cancer risk in women of reproductive age.
Study results show increased hydration can prevent recurrent cystitis Subscription
Increased water intake can help prevent cystitis and reduce antibiotic use in women with recurrent infections who drink less than 1.5 litres of fluid a day, study results have shown.
Long-term maintenance interventions needed for sustained blood pressure controlSubscription
Research has shown that the benefits of a pharmacist-led intensive telemonitoring protocol for blood pressure (BP) control lasted for up to a year after the end of the intervention.
Reminder apps improve self-reported adherence to cardiovascular medicinesSubscription
Medicine reminder apps can improve self-reported adherence to cardiovascular medicines, according to findings from a randomised clinical trial presented at the European Society of Cardiology Congress.
Lack of evidence to support statin use in non-cardiovascular conditionsSubscription
There is a lack of ‘convincing’ evidence that statins improve outcomes in non-cardiovascular conditions, such as diabetes, a review has shown.
Pharmacist prescribing support releases GP capacity, Scottish project showsSubscription
Prescribing support from specialist pharmacy staff could free up GPs’ time and capacity, results from a pilot project in Scotland have shown.
Point-of-care testing can support antimicrobial stewardshipSubscription
Researchers say the integration of point-of-care testing could help identify lower-risk patients in hospitals and subsequently reduce antibiotic use.
Daily vaping increases heart attack riskSubscription
Despite e-cigarettes being recommended as a safer alternative to tobacco smoking, researchers found data linking both e-cigarette use and cigarette smoking with a higher risk of myocardial infarction compared with not smoking.
