Research

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Substandard and falsified medicines: global and local efforts to address a growing problemSubscription

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Substandard and falsified medicines pose a risk to public health all around the world.

Insight

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‘One-size-fits-all’ treatment targets harm frail older patients with diabetesSubscription

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HbA1c targets that ignore differences in the physiology of older patients put them at risk of severe hypoglycaemia, harm and death.

CPD article

Early lesions from Stevens–Johnson syndrome

Stevens–Johnson syndrome and toxic epidermal necrolysisSubscription

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Practical guidelines for the treatment and management of Stevens–Johnson syndrome and toxic epidermal necrolysis, rare but life-threatening conditions that are normally caused by drugs or infections.

Research briefing

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Triple-combination therapy prevents drug resistance in colorectal cancer cellsSubscription

7 MAY 2019

Treating colorectal cancer with a trio of targeted drugs reduces the acquisition of drug resistance, in vitro research published in Oncogene shows.

busy hospital waiting room

Depression under-recognised in older adults during acute hospital staysSubscription

18 APR 2019

Diagnosis of depression is infrequently recorded on older adults’ patient notes, a survey of 27 acute hospitals across England has shown.

Older person's bedside with medicines

Sleeping tablets linked to increased antihypertensive useSubscription

17 APR 2019

Older adults with hypertension who take sleeping tablets are more likely to receive an increased number of antihypertensive medicines over time, study results have shown.

Pregnant woman taking a tablet

Painkiller link to childhood asthma unlikely to be causal, researchers saySubscription

15 APR 2019

A previously reported association between analgesic use in pregnancy and childhood asthma is likely to result from confounding factors, researchers have concluded.

Short communications

Piloting an undergraduate student-led health check serviceSubscription

There is a growing focus on the development of communication and clinical skills during undergraduate pharmacy programmes; this has been demonstrated particularly by the General Pharmaceutical Council’s recent consultation on initial education and training

Reducing cephalosporin-related supply errorsSubscription

Cephalosporins are a class of beta-lactam antimicrobials that exert bactericidal effects through disruption of the bacterial cell wall. These broad-spectrum antimicrobials have played a core role in the treatment of severe infections since their launch in the latter half of the 20th century. Early generation cephalosporins provide robust coverage of Gram-positive bacteria, while the newer third- and fourth-generations offer additional Gram-negative coverage, including Pseudomonas ...

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