Around 12,500 strokes are caused by atrial fibrillation (AF) in the UK each year, and 7,100 of these are preventable with appropriate anticoagulation. Four new oral anticoagulants (NOACs) are now available in the UK in addition to warfarin.
A lack of funding for research into chronic obstructive pulmonary disease, as well as difficulties in conducting clinical trials, make finding new treatments for this respiratory condition challenging. But there are glimmers of hope, such as reversing steroid resistance and identifying subpopulations of patients in order to speed up clinical trials.
Seeking a cure for HIVSubscription
Efforts to find a cure for HIV were reinvigorated in 2008 when the case of Timothy Ray Brown showed that a cure is possible. Researchers and pharmaceutical companies are now seeking out the virus in its hiding places in an attempt to eradicate it completely.
Personalised treatment for depression on the horizon: predicting response to antidepressantsSubscription
Only one-third of patients with depression benefit from the first antidepressant they try, but researchers are striving to find biological features that predict how a person will respond to particular drugs so they can tailor treatment from the beginning.
Conventional therapies and emergent precision medicines for cystic fibrosis: challenges and opportunitiesSubscription
Around 27 years ago, the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene – responsible for causing cystic fibrosis (CF) – marked a significant moment in the history of the condition. Despite the early promise of this target for gene therapy, a universally successful treatment has proven elusive in the ensuing years. While clinical trials involving gene therapy continue to make progress, the ‘magic bullet’ remains some way off. Survival continues to ...
A patient came into our pharmacy requesting an emergency supply of a salbutamol inhaler recently. He lives elsewhere but was working locally. We accessed his summary care record (SCR) and, to our surprise, discovered that he had not been prescribed anything since 2015. Before then, he was regularly prescribed beclomethasone and salbutamol inhalers. In addition, the surgery details he provided were incorrect.
Anti-cytokine drugs typically prescribed to treat inflammatory conditions, such as rheumatoid arthritis and psoriasis, can also improve symptoms of depression, according to new research.
The number of prescriptions for drugs to treat type 2 diabetes dispensed by community pharmacies in England rose by 33% over the past five years, according to research carried out by EXASOL, a database developer and analytics company.
Four types of commonly prescribed blood pressure medicines may have an impact on mood disorders such as depression or bipolar disorder, according to research.
A review scheme led by a team of pharmacists prevented an estimated 886 strokes in patients with atrial fibrillation.
Questionnaires sent to 112 patients with diabetes across 24 GP surgeries reveal a reluctance to improve lifestyle, as well as a lack of understanding about HbA1c levels.
When used during respiratory illness in children, paracetamol is not associated with a higher risk of asthma exacerbations than ibuprofen.
Regina Ahmed has decided to try a career in the primary care sector. In the first of a series of blog posts, she describes her first impressions of the role.