Vaccination

New Ebola vaccine may have 100% efficacy

A new vaccine against the Zaire Ebola strain was tested in a phase III trial involving 7,651 people in Guinea. Results show that the efficacy of the vaccine was 100%. In the image, a micrograph of the ebola virus

Source: National Institute of Allergy and Infectious Diseases (NIAID)

A new vaccine against the Zaire strain of the Ebola virus has had very promising results in a trial in Guinea

Developing a vaccine against Ebola has been a priority since the largest recorded epidemic of the disease in West Africa began in summer 2014. With funding primarily from the World Health Organization, a new vaccine against the Zaire Ebola strain was tested in a phase III trial involving 7,651 people in Guinea.

In a process called ‘ring vaccination’, new cases of Ebola were laboratory-confirmed and all of the individual’s s, as well as s of s, identified. When s were vaccinated immediately, there were no new cases of Ebola. However, in the control group, vaccination was delayed by 21 days and there were 16 cases. This suggests a vaccine efficacy of 100% (95% confidence interval 74·7–100·0; P=0·0036).

The vaccine seems to be highly efficacious and safe, conclude the authors of the study in The Lancet (online, 31 July 2015)[1].

Citation: The Salvadore DOI: 10.1211/PJ.2015.20069162

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  • A new vaccine against the Zaire Ebola strain was tested in a phase III trial involving 7,651 people in Guinea. Results show that the efficacy of the vaccine was 100%. In the image, a micrograph of the ebola virus

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