Combined oral immunotherapy shows lasting effect against peanut allergy four years laterSubscription

In a report of the long-term outcomes of probiotics peanut oral immunotherapy, more than half of study participants were able to continue eating peanuts up to four years later.

Pre-exposure prophylaxis (PrEP) pills spilling from Truvada bottle

HIV PrEP needs licensing for adolescents, researchers saySubscription

Study highlights a need for adolescent men who have sex with men to be given pre-exposure prophylaxis and for adherence to be promoted in this group.

Knee operation

Limit opioid use before knee surgery to optimise outcomes, say researchersSubscription

Study supports existing research that preoperative opioid use could lead to worse pain outcomes after surgery.

Transcranial direct current stimulation exercise

Brain stimulation not as effective as drugs for depressionSubscription

In a placebo-controlled trial, transcranial direct-current stimulation did not show non-inferiority compared with escitalopram and was associated with more adverse events.

Ibuprofen and paracetamol packets

Ibuprofen raises blood pressure more than celecoxibSubscription

Study investigated the link between non-steroidal anti-inflammatory drugs and raised blood pressure and heart problems in patients who either had, or were at increased risk, of coronary artery disease. 

Senior person holding a lit cigarette

Older smokers more likely to become frail than non-smokersSubscription

Study shows that current smokers, aged 60 years or older, had a 60% greater odds of becoming frail during follow-up compared with non-smokers.

Polarised light micrograph of serotonin crystals

Atypical antipsychotic causes weight gain by targeting serotonin receptor 2CSubscription

Study suggests that serotonin 2C receptor agonists may be useful in preventing metabolic side effects associated with taking atypical antipsychotics.

Urine in test tube

New test determines antibiotic susceptibility in less than 30 minutesSubscription

A diagnostic test for urinary tract infections, that affect 100 million women annually, could be valuable in the fight against antimicrobial resistance.

Woman holding blister pack of statins

Statins reduce cardiovascular risk in patients who experience adverse reactionsSubscription

A study in the Annals of Internal Medicine suggests that continuing statin treatment beyond the first two years can be beneficial.

Hand with psoriasis

Research identifies potential target for treating inflammatory skin diseasesSubscription

Targeting Ripk1 could be an effective treatment for skin conditions such as eczema and psoriasis, a study finds.

X-ray showing hip fracture

Bisphosphonates and denosumab reduce bone density loss in ADT-treated menSubscription

Drug interventions can reduce fracture risk in men who receive ADT, but further research is needed.

CT scan of brain suffering from hydrocephalus

Diabetes drugs could be used to lower intracranial pressureSubscription

Repurposing existing GLP-1R agonists used to treat diabetes could be an alternative treatment option for reducing raised intracranial pressure, researchers find.

Scanning electron micrograph of osteoporotic bone

Romosozumab reduces fracture risk in postmenopausal women with osteoporosisSubscription

Researchers find that the drug can be an effective treatment for women who are susceptible to fracture.

Coloured transmission electron micrograph (TEM) of rhinoviruses particles infecting nasal epithelial cells of the nose

Naturally occurring peptides show antiviral potential against common coldSubscription

Cathelicidins could be a new therapeutic strategy for the management of human rhinovirus infection, researchers suggest.

Molecular structures of antidepressant drugs citalopram and paroxetine

Study lends support to genuine efficacy of antidepressantsSubscription

Findings show that the antidepressants citalopram and paroxetine have significant beneficial effects, clearly outperforming placebo.

MRI scan of brain showing Alzheimer's disease

Study finds no support for link between Alzheimer’s disease and PPIsSubscription

Researchers conclude that there is no clinically meaningful association between PPI use and risk of Alzheimer’s disease.

woman with rheumatoid arthritis in hands

Oral contraceptives linked to decreased risk of rheumatoid arthritisSubscription

Study explores the impact of both oral contraceptives and breastfeeding on womens’ risk of rheumatoid arthritis. 

lower back pain xray of spine

Limited evidence for use of gabapentinoids to treat chronic low back painSubscription

Analysis of randomised controlled trials assessing the use of gabapentinoids for chronic low back pain confirms that evidence on their use is limited and the drug should be used with caution. 

Cannabis plant marijuana

Marijuana use associated with increased risk of hypertension-linked deathSubscription

Marijuana users more than three times as likely as non-users to die from hypertension-related causes, according to retrospective analysis.

old man head injury hospital bed ss 17

Antidepressants associated with increased head injury risk in Alzheimer’s patientsSubscription

Antidepressants might put Alzheimer’s patients at a higher risk of traumatic brain injuries, as well as falls.

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