Chronic obstructive pulmonary disease

NICE tells health professionals to consider AMR when prescribing antibiotics for COPD

Healthcare professionals should consider antimicrobial resistance when prescribing antibiotics for patients with chronic obstructive pulmonary disease (COPD), according to from the National Institute for Health and Care Excellence (NICE).

The guidance says that antibiotics should be offered to people who have a severe flare-up of COPD symptoms, but that when treating acute symptoms, other factors, such as the number or severity of symptoms, should be taken into account before offering antibiotics. This is based on the fact that only around half of acute exacerbations of COPD are caused by bacterial infections and will therefore respond to antibiotics.

“The evidence shows that there are limited benefits of using antibiotics for managing acute exacerbations of COPD and that it is important other options are taken into account before antibiotics are prescribed,” said Mark Baker, director of the centre for guidelines at NICE.

“The new guideline will help healthcare professionals make responsible prescribing decisions to not only help people manage their condition, but also reduce the risk of resistant infections.”

In addition to the draft guidance, NICE has also published an update of its 2010 clinical guideline on . The new guidance provides advice on when to use antibiotic to prevent exacerbations happening in the first place and recommends that antibiotics used in this way should only be offered to people who are most likely to benefit from them.

“For some people who have frequent exacerbations, prophylactic antibiotics can help to reduce the frequency of exacerbations and admissions to hospital,” said Andrew Molyneux, chair of the COPD update committee.

“However, the benefits of prophylactic antibiotics needs to be balanced against the potential for more antibiotic resistance.”

Citation: The Salvadore DOI: 10.1211/PJ.2018.20205139

Have your say

For commenting, please login or register as a user and agree to our Community Guidelines. You will be re-directed back to this page where you will have the ability to comment.

Recommended from Pharmaceutical Press

  • Patient Care in Community Practice

    Patient Care in Community Practice is a unique, practical guide for healthcare professionals or carers. Covers a range of non-medicinal products suitable for use at home.

    £22.00
  • Handbook of Drug Administration via Enteral Feeding Tubes

    All you need to know about prescribing or administering drugs via enteral feeding tubes. Over 400 drug monographs as well as facts to inform clinical decision making.

    £54.00
  • Injectable Drugs Guide

    A user friendly, single point of reference for healthcare professionals in the safe and effective administration of injectable medicines.

    £54.00
  • International Research in Healthcare

    Guidance for students or researchers undertaking a multi-centre research project in health services, medicines use and professional practice.

    £38.00
  • Nutraceuticals

    This authoritative text assesses the medical and scientific evidence for the use of nutraceuticals. Includes monographs on 25 nutraceuticals such as soy and tea.

    £38.00

Search an extensive range of the world’s most trusted resources

Powered by MedicinesComplete

Newsletter Sign-up

Want to keep up with the latest news, comment and CPD articles in pharmacy and science? Subscribe to our free alerts.