Issue : PJ November 2015 online

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  • Patients with subarachnoid haemorrhage (SAH) developing stress-induced cardiomyopathy (SIC), coloured x-ray pictured. Research found that these patients had higher peak levels of the cardiac damage peptides hsTnT and NTproBNP

    Two peptides predict cardiomyopathy after brain haemorrhage Subscription

    3 DEC 2015 11:06

    Swedish PhD student finds biomarkers that can identify subarachnoid haemorrhage patients at risk of cardiomyopathy.

  • Research shows a blood test could predict which antidepressant will work for each patient. In the image, blood from tests ready to be analysed

    Blood test could show whether an antidepressant is effective, research suggests Subscription

    2 DEC 2015 9:52 By Bea Perks

    Psychiatrists could be on the way to developing a test that predicts which patients with depression will benefit from which antidepressant.

  • Necitumumab (Eli Lilly’s Portrazza) has been approved by the US drugs safety watchdog for patients with advanced squamous non-small cell lung cancer (NSCLC), image attached, who have not received other treatment for their advanced disease

    FDA approves necitumumab for non-small cell lung cancer Subscription

    1 DEC 2015 15:19

    Necitumumab (Portrazza) has been approved by the US drugs safety watchdog as a new combination therapy for patients with advanced squamous non-small cell lung cancer who have not received other treatment for their advanced disease.

  • Researchers have found that the glucagon-like peptide-1 analogue liraglutide – a treatment for type 2 diabetes – is also effective in non-alcoholic steatohepatitis (NASH), micrograph pictured

    Diabetes treatment effective in liver disease Subscription

    30 NOV 2015 16:41

    Almost two fifths of patients given liraglutide had resolution of the common liver disease called NASH.

  • Pharmacist Rob Morris (pictured) has spent his career developing and selling medicines for farm animals and pets. He encourages other pharmacists to consider the sector, even though jobs may be scarce.

    Why I chose veterinary pharmacy instead of community or hospital Subscription

    30 NOV 2015 16:16 By Rob Morris

    Practising veterinary pharmacy offers flexibility and creativity that the traditional sectors do not, writes Rob Morris.

  • NICE does not recommend apremilast Subscription

    30 NOV 2015 15:44

    The National Institute for Health and Care Excellence (NICE) does not recommend apremilast (Otezla; Celgene) for treating some adults with moderate to severe chronic plaque psoriasis.  

  • NICE recommends pembrolizumab Subscription

    30 NOV 2015 15:42

    The National Institute for Health and Care Excellence (NICE) recommends pembrolizumab (Keytruda; Merck, Sharp & Dohme) as a treatment option in adults with advanced melanoma that has not been previously treated with ipilimumab when the company provides pembrolizumab with the discount agreed in the patient access scheme.

  • New NICE recommendations for hepatitis C Subscription

    30 NOV 2015 13:52

    The National Institute for Health and Care Excellence has published final guidance recommending ledipasvir-sofosbuvir (Harvoni; Gilead Sciences), ombitasvir-paritaprevir-ritonavir with or without dasabuvir (Viekirax ...

  • NICE recommends vortioxetine Subscription

    30 NOV 2015 13:47

    The National Institute for Health and Care Excellence (NICE) has published final guidance that recommends vortioxetine (Brintellix; Lundbeck, Takeda) as third-line treatment for major depressive episodes. Vortioxetine should be considered as a treatment option for adults whose condition has responded inadequately to two antidepressants within the current episode.

  • Caution with concomitant Zelboraf and radiation treatment Subscription

    30 NOV 2015 13:42

    The summary of product characteristics for Zelboraf (vemurafenib; Roche) now states that cases of radiation recall and radiation sensitisation have been reported in patients treated with radiation either prior, during, or subsequent to vemurafenib treatment. Therefore, vemurafenib should be used with caution when given concomitantly or sequentially with radiation treatment.

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